1. It is also used as preventive treatment against Neisseria meningitidis (meningococcal) infections.

2. Search for a preventive treatment for the disease has been greatly aided by advances in molecular genetics.

3. The use of chemically synthesised allopathic veterinary medicinal products or antibiotics for preventive treatment is prohibited, without prejudice to Article 24(3).

4. We also provide hygienic and preventive treatment. Our experience of several years allows us to cope with difficult clinical cases resulting from inborn or acquired defects.

5. According to the relative frequency of organoacidurias and the option of preventive treatment for patients with glutaric aciduria type I, organic acid analysis should be performed vigorously also in neurologically asymptomatic patients with unclear macrocephaly.