1. The prenatally Androgenized (PNA) rat model was established

2. Bartter syndrome can manifest prenatally with intrauterine growth restriction and polyhydramnios

3. Endocrine Traits of Polycystic Ovary Syndrome in Prenatally Androgenized Female Sprague-Dawley Rats

4. The only component missing from prenatally Androgenized female monkeys is insulin resistance independent of obesity.

5. In Denmark, between 1970 and 1984, 76% of the prenatally diagnosed fetuses with triple-X were aborted.

6. However, prenatally Androgenized female rhesus monkeys exhibit ovarian and endocrinological features that mimic those found in women with PCOS

7. We propose that the disruption of ovarian function in prenatally-Androgenized sheep is mediated via follicular defects stemming from reduced intrafollicular activin availability/action.

8. Adult prenatally-Androgenized (PNA) mice exhibit increased GnRH neuron firing rate, elevated ovarian androgens, and disrupted cycles, but before puberty, GnRH neuron activity is reduced in PNA mice compared with controls

9. To examine muscular changes in a prenatally Androgenized (PNA) rat model for PCOS, Sprague–Dawley rats were exposed to 5 mg testosterone or vehicle daily on gestational days 16–19

10. Presented is a case of congenital agenesis of the M3 and prenatally formed enamel and coronal dentine hypoplasia of the M1 in the lower jaw of a roe buck, aged about 18 months.

11. Most of these abnormalities had previously been described in prenatally diagnosed cases of partial or complete trisomy 17p [6, 7], except the cystic dilation of the Aqueductus Sylvii associated with dilation of the 4th ventricle, and this is a new observation.

12. Prenatally Androgenized female rhesus monkeys provide a close phenotypic mimic of PCOS in women, suggesting that the age of initial androgen excess may be a basic component in the differentiation of the syndrome (Figure 2)

13. The Androgenized females exhibit approximately 40–50% fewer menstrual cycles than normal females , with normal females undergoing 5–8 menstrual cycles during the 6 month period illustrated, while early-treated prenatally Androgenized females range from 0–5 cycles and late-treated females range from 0–7.

14. Adult, prenatally Androgenized female rhesus macaques (female pseudohermaphrodites) that had been ovariectomized were treated with estradiol benzoate (20 μg/day) and paired with males at weekly intervals for 4 weeks beginning on Day 12 of injection. Their sexual behavior was compared to that of a control group of females.