1. A method of treating myotonic dystrophy

2. Molecular studies revealed a trinucleotide amplification at the myotonic dystrophy locus 19q13.3, so the diagnosis myotonic dystrophy Curschmann-Steinert was established.

3. We recorded myotonic discharges electromyographically in 5 patients with myotonia congenita and in 8 others with myotonic dystrophy.

4. Myotonia congenita and myotonic dystrophy were not aggravated by cooling.

5. The invention relates to Drosophila transgenic animal models for myotonic dystrophies.

6. Left ventricular hypertrabeculation (LVHT) has not been described in myotonic dystrophy Type I (MD1) before.

7. Methods and compositions comprising ampk activator (metformin/troglitazone) for the treatment of myotonic dystrophy type 1 (dm1)

8. Avidity's lead product candidate, AOC 1001, is designed to treat myotonic dystrophy type 1, and its other muscle programs are focused on the treatment of Duchenne muscular dystrophy

9. When the extracellular K+ concentration is elevated the duration of the warmed-up state is diminished and the maximal amplitude of the myotonic contraction is reduced by 27%.

10. A 25-year-old male patient is described, who first experienced episodes of what resembled adynamia episodica (Gamstorp) toward the end of the first decade of his life, later accompanied by myotonic and slight paramyotonic symptoms.

11. By comparing biopsies of autosomal dominant, autosomal recessive myotonia congenita, paramyotonia congenita, paramyotonia congenita, adynamia episodica hereditaria with myotonia, and myotonic dystrophy by light and electron microscopy, various alterations were observed, most of which however were non-specific.